The rate of E-to-A conversion and the proportions of the different A varieties synthesized in vitro were much like these noticed for the tissues in vivo at comparable instances. These results suggest that the post translational processing in vitro was much like that in vivo. The data have been in keeping with the possibility that the increase in synthesis of A forms occurred either in cells that had previously synthesized E types or in a distinct population of cells that already synthesized A varieties. In pulse-chase experiments, the E type of N-CAM that was synthesized in the course of the first day after explantation continued as E form for several days, at occasions when newly synthesized N-CAM was predominantly in A varieties.
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- Altered expression of neuronal cell adhesion molecules induced by nerve injury and repair.
- Alterations in neural cell adhesion molecules throughout development of various regions of the nervous system.
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- The neural cell adhesion molecule (N-CAM) inhibits proliferation in major cultures of rat astrocytes.
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Data that is available consists of informati… The neural cell adhesion molecule (N-CAM) inhibits proliferation in primary cultures of rat astrocytes. The mechanism of binding of neural cell adhesion molecules.